Myotonic Dystrophy Type 2. It appears to be important for the correct functioning of cells in the heart brain and skeletal muscles which are used for movement. DM2 is an important diagnosis to consider in patients who have proximal muscle weakness around.
The format is GTR000000011 with a leading prefix GTR followed by 8 digits a period then 1 or more digits representing the version. The term myotonic comes from several words in Greek. The most common symptoms are muscle weakness and pain myotonia and cataracts.
DM2 is an important diagnosis to consider in patients who have proximal muscle weakness around.
Myotonic dystrophy type 2 one of the two types of myotonic dystrophy is an inherited muscular dystrophy that affects the muscles and other body systems eg heart eyes and pancreas. The specific kinds of mutations found in both types of myotonic dystrophy are trinucleotide repeat expansionsThese types of mutations occur when a piece of DNA is abnormally repeated a number of times which makes the gene unstable. Myotonic dystrophy type 2 DM2 is characterized by myotonia and muscle dysfunction proximal and axial weakness myalgia and stiffness and less commonly by posterior subcapsular cataracts cardiac conduction defects insulin-insensitive type 2 diabetes mellitus and other endocrine abnormalities. They result in multisystem disorders characterized by skeletal muscle weakness and myotonia difficulty relaxing muscles after use cardiac abnormalities cataracts and other abnormalities.
